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Mesothelioma and Non Asbestos Exposure Mesothelioma typically develops in the lung's lining (pleura) and abdomen (peritoneum). The rare cancer may also form in the linings of the heart or testes (pericardium). Asbestos exposure is a major risk factor for mesothelioma. However, some people diagnosed with mesothelioma do not have a history of asbestos exposure. Exposure to Asbestos Asbestos, a rock that is of natural origin was used in the past to make industrial and construction materials all over the world. Workers working in asbestos-related industries were exposed to asbestos on a daily basis. Asbestos particles can be trapped in the lungs, which can lead to progressive lung disease. This is referred to as asbestosis. As time passes, these trapped fibers can cause mesothelioma as well. Asbestos is also inhaled or eaten, and the risk of developing mesothelioma and other asbestos-related illnesses increases with the amount and length of exposure. Most cases of mesothelioma result from occupational exposure. Asbestos was used in many trades, including construction, insulation electrical work, automotive maintenance and pipefitting. These occupations are generally dominated by men, and as a result, male mesothelioma cases comprise 75-80% of all reported cases. However, the phasing out of asbestos in the United States and other first-world countries has reduced exposure to asbestos on the job. This has led to an increase in cases with non-occupational exposure becoming more prevalent. Non-occupational mesothelioma may occur when asbestos is released from a work environment or in the home or school environment. Secondhand exposure can also cause it, such as when a family member touches the work clothes of a asbestos worker. Palatine asbestos lawsuit who experience this type of exposure might experience symptoms such as breathing problems or chest pain, which is commonly mistaken for lung or heart problems. Some studies have linked mesothelioma with non-occupational exposures, but the results vary. Many of these studies have been conducted on a small sample size, and between-study heterogeneity has been high. It is essential to conduct more research to establish the link between asbestos exposure in non-occupational settings and mesothelioma. Those with non-occupational exposure should discuss their asbestos background with their doctor. They should request mesothelioma testing when they are concerned and request an appointment with an expert. Mesothelioma specialists are able to provide patients with the best treatment and care options to improve their chances of survival. They will review medical records and conduct imaging tests to determine the disease. They will also provide guidance on how to file mesothelioma suits to get compensation from asbestos trust funds. Secondhand Exposure Although asbestos exposure is the primary cause of mesothelioma not the only way to get this cancer. There is evidence that people who haven't handled asbestos or worked in industries with asbestos-related activities can still develop mesothelioma. This is called secondary or non-occupational exposure to asbestos. Asbestos fibres are very small and can adhere to hair, clothing, and skin. In the end, workers may bring the harmful fibers home on their work clothes and then transfer them to family members. These asbestos fibers could be inhaled or swallowed, which can lead to mesothelioma. The mesothelioma type is found more frequently in women and usually in the lung. However, it can be found in the abdomen and chest wall. The most common sign is a shortness of breath (dyspnea), and it is often accompanied by other symptoms like fluid in the lungs or swelling in the scrotum. The mesothelioma that develops in the lungs is called mesothelioma of the pleural region. Mesothelioma affecting the chest wall or stomach is referred to as mesothelioma of the peritoneal region. This kind of mesothelioma could cause a number of symptoms, including abdominal pain, difficulty in breathing, and constipation. According to a variety of studies, individuals who have not been exposed to asbestos while at work can still develop mesothelioma due to exposure through secondhand sources. These individuals usually lived with someone who was exposed to asbestos. They may have touched the clothing of the worker, or they might have been in contact with asbestos in other ways. Veterans are at a high risk of developing mesothelioma due to the extensive use of asbestos in military bases, ships and vehicles. The Navy is at a greater risk since asbestos was used in the hulls and gun turrets on ships to protect them from fire. Asbestos was also often brought home by sailors who had returned from their duties aboard ships that had been contaminated. Environmental Exposure A variety of substances have been associated with mesothelioma. However, the disease is most often associated with exposure to asbestos. Asbestos, a naturally occurring mineral was used in the manufacturing process for many years. It is a heat-resistant material and durable making it ideal for insulation, brakes, shingles, flooring, and other products. Asbestos is broken down to dust that can be inhaled and swallowed. These fibers may remain in the lungs and stomach for a long time, triggering mesothelioma-related symptoms. The most frequent mesothelioma symptoms are chest pain as well as abdominal discomfort, and difficulty breathing. Asbestos exposure can cause these symptoms to last for up to 60 years. It is important to consult a doctor when you experience these symptoms. Telling your doctor about asbestos exposure is essential. This can help avoid a false diagnosis and ensure that you receive the correct treatment. The most commonly affected mesothelioma victims from asbestos exposure are those who have worked directly with asbestos but it is possible for loved ones to be affected. This is referred to as secondary exposure. Family members can inhale or ingest asbestos fibers from a worker's clothing, shoes, or tools. They could be sprayed on the home by someone wearing or having their hair. It is for this reason that mesothelioma sufferers and their families must wash their clothes properly after working with asbestos. There is a substantial collection of studies that show the connection between exposure to asbestos and mesothelioma, but there is no conclusive evidence yet about the role of other agents. For example, there is some evidence that the zeolites erionite and chrysotile can cause mesothelioma. Erionite is present in the soil and rocks of certain parts in Turkey where the rate of mesothelioma pleural is high. The study of the relationship between asbestos and mesothelioma is in progress. Funnel plots have indicated the potential for bias in publication, and between-study heterogeneity is very high. However, it is still evident that occupational exposure to asbestos is the most significant risk factor for mesothelioma. Genetics Mesothelioma is a rare disease caused by malignant mesothelial cells which expand beyond control and invade surrounding tissues. It can also expand throughout the body through traversing the lymphatic system or bloodstream and affecting other organs. Although asbestos is the principal cause of mesothelioma, it isn't the only risk factor. Other genetic and environmental factors can trigger the condition. In some instances mesothelioma has been found in people who had no direct exposure to asbestos. They are known as non-occupational mesothelioma patients. They are typically exposed indirectly by the handling of harmful household items or clothing by anyone who was exposed to asbestos in their home. It is possible to be diagnosed with mesothelioma following inhaling asbestos fibers from clothing of a family member. Studies show that these types of mesothelioma cases tend to have longer latency times and are more likely to be diagnosed in wives than in husbands. Scientists are currently studying the possibility that a genetic predisposition to mesothelioma might play a role in the development of the disease. Recent studies have demonstrated that mutations in BAP1, a gene, can increase the risk of mesothelioma among those who have been exposed to asbestos. This is a significant finding, as it could be the basis for improved screening procedures for those at risk of developing mesothelioma. Researchers have identified a variety of genes that are linked to mesothelioma. Some of these genes are involved in limiting tumor growth and are often mutated or altered in mesothelioma patients. These genes include large tumor suppressor 2 (LATS2) and NF2. People who have mesothelioma-related family history are at a higher chance of contracting the disease. This is due to certain genes, such as the BAP1 gene, can be passed down from an individual parent. Veterans have the highest mesothelioma rate when compared to other occupational categories due to asbestos being used extensively in the military. People who were in the Navy and on ships were at greatest risk due to the high exposure to asbestos in fireproofing, insulation materials and shipbuilding.